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Young women with PCOS often have elevated insulin levels and are more likely to develop diabetesMetformin is a medication often prescribed for women with PCOS to help prevent diabetesA lifestyle that includes healthy nutrition and daily exercise is the most important part of a PCOS treatment plan.

Metformin reduces the amount of sugar your liver releases into your bloodIt also makes your body respond better to insulinInsulin is the hormone that controls the level of sugar in your blood.

Reducing the amount of glucosesugarmade by your liver decreasing the amount of glucose your body absorbs increasing the effect of insulin on your body.

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in a 24-week placebo-controlled factorial study of initial therapy, sitagliptin 50 mg twice daily in combination with metformin 500 mg or 1,000 mg twice daily provided significant improvements in glycaemic parameters compared with either monotherapy.

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