Among others, it has agonistic enhancing effect on serotonin receptor type 1a or 5ht1a like buspar , a reuptake inhibitor of both serotonin and norepinephrine like imipramine or tofranil and venlafaxine or effexor , and it blocks serotonin receptor 1d 5ht1d , also proposed to be a mode of antidepressant action.
Information about Tofranil.
Take our 2-minute Attention Deficit Hyperactivity Disorder quiz to see if you may benefit from further diagnosis and treatment.
Following prolonged therapy with high dosesabrupt discontinuation of TCAsincluding imipraminecould lead to withdrawal symptoms such as nauseavomitingdiarrheaor restlessnessThereforemany experts recommend gradually reducing the dose of drug if the drug is to be discontinued.
People with bulimia nervosaan eating disorder that involves episodes of bingeing and purgingexperience symptoms and signs.
Before using this medicationtell your doctor or pharmacist your medical historyespecially ofbreathing problemse.gasthmachronic bronchitispersonal or family history of glaucomaangle-closure typediabeteseating disorderse.gbulimiaheart problemse.garrhythmiascoronary artery diseaseliver problemskidney problemspersonal or family history of other mental/mood conditionse.gbipolar disorderschizophreniaseizuresoveractive thyroidhyperthyroidismtrouble urinatinge.gdue to enlarged prostateany condition that may increase your risk of seizurese.galcohol/sedative dependencyuse of electroconvulsive therapybrain injury/disease such as strokecertain types of tumorse.gpheochromocytomaneuroblastoma
Anxiety or agitation are possible side effects of TofranilSometimes antidepressants can cause or increase suicidal thoughts in children or adultsIf you have a personal history or family history of bipolar disordertalk to your doctor about the risks.
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