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Oral administration of doxycycline to male and female sprague-dawley rats adversely affected fertility and reproductive performance, as evidenced by increased time for mating to occur, reduced sperm motility, velocity, and concentration, abnormal sperm morphology, and increased pre-and post-implantation losses.

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This document does not contain all possible side effects and others may occurCheck with your physician for additional information about side effects.

Overgrowth of non-susceptible organismsincluding fungimay occurif such infections occurdiscontinue use and institute appropriate therapy.

Your doctor may start you on a lowered dosage or a different scheduleThis can help keep levels of this drug from building up too much in your body.

The dosage information below is for the conditions that this drug is most often prescribed to treatThis list may not contain all conditions that your doctor can prescribe this drug forIf you have questions about your prescriptiontalk with your doctor.

Antibiotic-associated diarrheaSymptoms can includesevere diarrhea bloody diarrhea stomach cramping and pain fever dehydration loss of appetite weight loss High blood pressure inside your skullSymptoms can includeheadache blurry vision double vision vision loss Irritation of your esophagus or ulcers in your esophagusmay be more likely if you take your dose at bedtimeSymptoms can includeburning or pain in your chest Anemia PancreatitisSymptoms can includepain in your upper abdomenor pain in your abdomen that moves to your back or gets worse after you eat fever Serious skin reactionsSymptoms can includeblisters peeling skin a rash of small purple spots.

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studies have shown no significant difference in serum half-life of doxycycline range 18-22 hours in individuals with normal and severely impaired renal function.

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