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Carbamazepine tegretol may reduce the effect of bupropion by reducing the blood concentration of bupropion.

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Bupropion is a prescription drugIt comes in the form of an immediate-release tablet or an extended-release tabletBoth forms are taken by mouthAn extended-release drug is released into your system slowly over timeAn immediate-release drug works more quickly.

Do not use bupropion within 14 days before or 14 days after you have used a MAO inhibitorsuch as isocarboxazidlinezolidmethylene blue injectionphenelzinerasagilineselegilineor tranylcypromine.

You may have a higher risk of seizures if you use certain other medicines while taking bupropion.

Observe patients for neuropsychiatric symptomssuch as changes in behaviorhostilityagitationdepressed moodand suicide-related eventsincluding ideationbehaviorand attempted suicidesee Black Box Warningstherapy may cause delusionshallucinationspsychosisparanoiaconfusionand concentration disturbancesymptoms may abate with dose reduction.

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