Significant interaction between the nonprescription antihistamine diphenhydramine and the cyp2d6 substrate metoprolol in healthy men with high or low cyp2d6 activity.
Information about Toprol.
TOPROL-XLlike other beta-blocker medicinestends to decrease blood circulation in the skinfingers and toesIt may make you more sensitive to cold weatherespecially if you have circulation problems.
Have your blood pressure and pulseheart ratechecked regularly while taking this medicationLearn how to check your own blood pressure and pulse at homeand share the results with your doctor.
If you are not sure whether any of these apply to youcheck with your doctor.
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